Anomalies in the cognitive-executive functions in patients with Chiari Malformation Type I

• José Luis Besteiro González ^[1] ; José María Torres Campa-Santamarina
  1. [1] Universidad de Oviedo

     Universidad de Oviedo

     Oviedo, España

     
• Localización: Psicothema, ISSN-e 1886-144X, ISSN 0214-9915, Vol. 30, Nº. 3, 2018, págs. 316-321
• Idioma: inglés
• DOI: 10.7334/psicothema2017.401
• Títulos paralelos:
  • Anomalías en las funciones cognitivo-ejecutivas en pacientes con la Malformación de Chiari Tipo I
• Enlaces
  • Texto completo (pdf)
• Resumen
  • español

    . Antecedentes: en la última década, existen evidencias crecientes de que défi cits neuropsicológicos, esencialmente en funciones ejecutivas, pueden estar involucrados en la patogenia de la enfermedad de Chiari Tipo I. El objetivo del estudio es evaluar la infl uencia de anormalidades estructurales sobre las funciones neuropsicológicas, fundamentalmente ejecutivas, en pacientes con Chiari Tipo I. Método: para ello se comparó el perfi l neuropsicológico de estos pacientes con controles sanos. Tanto a los pacientes Chiari Tipo I como a los controles sanos se les aplicó pruebas neuropsicológicas que valoraron funciones ejecutivas frontales de vigilancia o atención sostenida, fl exibilidad mental, y planifi cación y formación de conceptos (Stroop, CPT, WCST). Resultados: los resultados obtenidos sugieren una afectación de los pacientes Chiari Tipo I en los procesos de inhibición y autocontrol (Stroop) y en la capacidad atencional y en el mantenimiento del curso del pensamiento y la acción (WCST). Conclusiones: estos resultados proporcionan evidencias de posibles défi cits o anomalías en las funciones ejecutivas cognitivas, que permitirían diferenciar los pacientes con Chiari Tipo I.

  • English

    Background: Over the last decade there has been growing evidence that neuropsychological defi cits, principally in the executive functions, may be involved in the pathogenesis of Chiari Type I disease. The aim of this study is to compare changes in cognitive function in patients with Chiari Type I and healthy subjects. Method: The neuropsychological profi le of these patients was compared with healthy controls. Three neuropsychological tests were administered to both Chiari Type I patients and healthy controls to assess the frontal executive functions of vigilance or selective attention, mental fl exibility, planning and concept formation. Results: The results suggest that Chiari Type I patients are affected in the processes of inhibition and self-control as well as in attention capacity and maintaining a course of thought and action. Conclusions: These results provide evidence of possible defi cits or anomalies in the cognitive executive functions of patients with Chiari Type I.

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