INECO Frontal Screening: an instrument to assess executive dysfunction in schizophrenia

• Tânia Silva ^[1] ; Luis Monteiro ^[1] ; Emanuela Lopes ^[2]
  1. [1] Instituto Superior de Ciências da Saúde Egas Moniz

     Instituto Superior de Ciências da Saúde Egas Moniz

     Caparica, Portugal

     
  2. [2] Centro Hospitalar do Alto Ave
• Localización: The Spanish Journal of Psychology, ISSN 1138-7416, Vol. 17, 2014, págs. 1-11
• Idioma: inglés
• DOI: 10.1017/sjp.2014.22
• Enlaces
  • Texto completo
• Resumen

  • Although several brief sensitive screening tools are available to detect executive dysfunction, few have been developed to quickly assess executive functioning. The INECO Frontal Screening (IFS) is a brief tool which has proved be useful for the assessment of the executive functions in patients with dementia. The aim of this study was to explore whether the IFS is as sensitive and specific as the BADS, a battery designed to assess the dysexecutive syndrome, in schizophrenia. Our sample comprised a group of 34 schizophrenic patients (Mean age = 39.59, DP = 10.697) and 31 healthy controls (Mean age = 35.52, DP = 10.211). To all groups were administered the BADS, Wisconsin Card Sorting Test and IFS. The results suggest that schizophrenic patients performed significantly worse than the control group in all tests (p < .05). The IFS total score was 13.29 for the experimental group and 26.21 for the control group (p < .001). Considering a cut-off of 14 points, the IFS sensitivity was 100% and specificity 56% in detection of executive dysfunction in schizophrenia, compared with the BADS, that if we consider a cut-off of 11 points, was a sensitivity of 100% and a specificity of 50%. Thus, IFS is a brief, sensitive and specific tool for the detection of executive dysfunction in schizophrenia.

• Referencias bibliográficas
  • Baddeley A. D. (1986). Working memory. Oxford, UK: Clarendon Press.
  • Bá ez S., Gleichgerrcht E., Urquina H. , Lischinsky A., Roca M., Manes F., & Torralva T. (2011, May). Utility of the INECO Frontal Screening...
  • Barbosa M., & Monteiro L. (2008). Recurrent criminal behavior and executive dysfunction. The Spanish Journal of Psychology, 11, 259-265.
  • Burgess P. W., & Shallice T. (1996). Bizarre responses, rule detection and frontal lobe lesions. Cortex, 32, 241-259. http://dx.doi.org/10.1016/S0010-9452(96)80049-9
  • Caldeira M. J. (2011). Adaptation and validation of INECO Frontal Screening (Master's Thesis). Instituto Superior de Ciěncias da Saúde-Norte:...
  • Carter C. S., Barch D. M., Bullmore E., Breiling J., Buchanan R. W., Butler P., ⋯ Wykes T. (2011). Cognitive neuroscience treatment research...
  • Chan R. C., Chen E. Y., & Law C. W. (2006). Specific executive dysfunction in patients with first-episode medication-naïve schizophrenia....
  • Clark L., & Manes F. (20 04). Social and emotional decisionmaking following frontal lobe injury. Neurocase, 10, 398-403. http://dx.doi.org/10.1080/13554790490882799
  • Clark L., Manes F., Antoun N., Sahakian B. J., & Robb ins T. W. (2003). The contributions of lesion laterality and lesion volume to decision-making...
  • Cornblatt B. A., Lenzenweger M. F., Dworkin R. H., & Erlenmeyer-Kimling L. (1992). Childhood attentional dysfunction predicts social isolation...
  • Crawford J. (1998). Introduction to the assessment of attention and executive function. Journal of Neuropsychological Rehabilitation, 8, 209-211....
  • Damasio A. R. (1995). Toward a neurobiology of emotion and feeling: Operational concepts and hypotheses. The Neuroscientist, 1, 19-25. http://dx.doi.org/10.1177/107385849500100104
  • Davidson M., Reichenberg A., Rabinowitz J., Weiser M., Kaplan Z., & Mark M. (1999). Behavioral and intellectual markers for schizophrenia...
  • Eisenberg D. P., & Berman K. F. (2010). Executive function, neural circuitry, and genetic mechanisms in schizophrenia. Neuropsychopharmacology,...
  • Eslinger P. J., & Grattan L. M. (1993). Frontal lobe and frontal-striatal substrates for different forms of human cognitive flexibility....
  • Ettlin T., & Kischka U. (1999). Bedside frontal lobe testing. The " frontal lobe score".In B. L. Miller, & J. L. Cummings...
  • Evans J. J., Chua S. E., McKenna P. J., & Wilson B. A. (1997). Assessment of the dysexecutive syndrome in schizophrenia. Psychological...
  • Everett J., Lavoie K., Gagnon J., & Gosselin N. (2001). Performance of patients with schizophrenia on the Wisconsin Card Sorting Test...
  • Folstein M. F., Folstein S. E., & McHugh P. R. (1975). Mini-mental State: A practical method for grading the cognitive state of patients...
  • Freedman D., & Brown A. (2011). The developmental course of executive functioning in schizophrenia. International Journal of Developmental...
  • Gioia G. A.,Isquith P. K.,Guy S. C.,Kenworthy L. 2000 BRIEF: Behavior rating inventory of executive function professional manual Lutz, FL:...
  • Goldberg T. E., David A., & Gold J. M. (2003). Neurocognitive deficits in schizophrenia. In S. R. Hirsch, & D. R. Weinberger (Eds.),...
  • Goldman-Rakic P. S. (1994). Working memory dysfunction in schizophrenia. The Journal of Neuropsychiatry and Clinical Neurosciences, 6, 348-357.
  • Graham S., Phua E., Soon C. S., Oh T., Au C., Shuter B., ⋯ Yeh I. B. (2009). Role of medial cortical, hippocampal and striatal interactions...
  • Green M. F., Kern R. S., & Heaton R. K. (2004). Longitudinal studies of cognition and functional outcome in schizophrenia: Implications...
  • Greve K. W., Stickle T. R., Love J. M., Bianchini K. J., & Stanford M. S. (2005). Latent structure of the Wisconsin Card Sorting Test:...
  • Groth-Marnat G. (2000). Neuropsychological assessment in clinical practice: A guide to test interpretation and integration. Hoboken, NJ: Wiley.
  • Heinrichs R. W., & Zakzanis K. K. (1998). Neurocognitive deficit in schizophrenia: A quantitative review of the evidence. Neuropsychology,...
  • Ihara H., Berrios G. E., & McKenna P. J. (2000). Dysexecutive syndrome in schizophrenia: A cross-cultural comparison between Japanese...
  • Jansma J. M., Ramsey N. F., van der Wee N., & Kahn R. S. (2004).Working memory capacity in schizophrenia: A parametric fMRI study. Schizophrenia...
  • Jonides J., Schumacher E. H., Smith E. E., Koeppe R. A., Awh E., Reuter-Lorenz P. A., ⋯ Willis, C. (1998). The role of parietal cortex in...
  • Keefe R., Goldberg T. E., Harvey P. D., Gold J. M., Poe M. P., & Coughenour L. (2004). The brief assessment of cognition in schizophrenia:...
  • Kerns J. G., Nuechterlein K. H., Braver T. S., & Barch D. M. (2008). Executive functioning component mechanisms and schizophrenia. Biological...
  • Koren D., Seidman L. J., Harrison R. H., Lyons M. J., Kremem W. S., Caplan B., ⋯ Tsuang M. T. (1998). Factor structure of the Wisconsin Card...
  • Krabbendam L., Vugt E., Derix M., & Jolles J. (1999). The Behavioral Assessment of the Dysexecutive Syndrome as a tool to as sess executive...
  • Lezak M. D., Howieson D. B., & Loring D. W. (2004). Neuropsychological assessment (4th Ed.). New York, NY: Oxford University Press.
  • Liddle P. F., & Morris D. L. (1991). Schizophrenic symptoms and frontal lobe performance. The British Journal of Psychiatry, 158, 340-345....
  • Manes F., Sahakian B., Clark L., Rogers R., Antoun N., Aitken M., & Robbins T. (2002). Decision-making processes following damage to the...
  • Miyake A., Friedman N. P., Emerson M. J., Witzki A. H., Howerter A., & Wager T. D. (2000). The unity and diversity of executive functions...
  • Norman D. A., & Shallice T. (1986). Attention to action: Willed and automatic control of behavior. In R. I. Davidson, G. E. Schwartz,...
  • Norris G., & Tate R. (2000). The Behavioral Assessment of the Dysexecutive Syndrome (BADS): Ecological, concurrent and construct validity....
  • Palmer B. W., & Heaton R. K. (2000). Executive dysfunction in schizophrenia. In T. Sharma & P. D. Harvey (Eds.), Cognition in schizophrenia:...
  • Palmer C.,Heiby E.,Fujii D.,Kameoka V. 2008 Executive functioning in schizophrenia: The contributions o f attention, working memory, processing...
  • Reeder C., Newton E., Frangou S., & Wykes T. (2004). Which executive skill s should we target to affect social functioning and symptom...
  • Rothli nd J. C., & Brandt J. (1993). A brief assessment of frontal and subcortical functions in dementia. Journal of Neuropsychiatry and...
  • Royall D. R., Mahurin R. K., & Gray K. F. (1992). Bedside assessment of executive cognitive impairment: The executive interview. Journal...
  • Shallice T. (1988). From neuropsychology to mental structure. Cambridge, UK: Cambridge University Press.
  • Shallice T., & Burgess P. W. (1991). Deficits in strategy application following frontal lobe damage in man. Brain, 114, 727-741. http://dx.doi.org/10.1093/brain/114.2.727
  • Snitz B. E., Macdonald A. W., & Carter C. S. (2006). Cognitive deficits in unaffected first-degree relatives of schizophrenia patients:...
  • Strauss E., Sherman E., & Spreen O. (2006). A compendium of neuropsychological tests: Administration, norms and commentary. (3rd Ed.)....
  • Stuss D. T., Alexander M. P., Shallice T., Picton T. W., Binns M. A., Macdonald R., ⋯ Katz D. I. (2005). Multiple frontal systems controlling...
  • Stuss D. T., & Benson D. F. (1986). The frontal lobes. New York, NY: Raven Press.
  • Szöke A., Schurhoff F., Mathieu F., Meart A., Ionescu S., & Lebover M. (2005). Tests of executive functions in firstdegree relatives of...
  • Tanibuchi I., & Goldman-Rakic P. S. (2003). Dissociation of spatial-, object-, and sound-coding neurons in the medio dorsal nucleus of...
  • Torralva T., Kipps C. M., Hodges J. R., Clark L., Bekinschtein T., Roca M., ⋯ Manes, F. (2007). The relationship between affective decision-making...
  • Torralva T., Roca M., Gleichgerrcht E., López P., & Manes F. (2009). INECO Frontal Screening (IFS): A brief, sensitive, and specific tool...
  • Wilson B. A., Alderman N., Burgess P. W., Emslie H. E., & Evans J. J., (1996). Behavioral assessment of the dysexecutive syndrome. Suffolk,...
  • Wilson B. A., Evans J. J., Emslie H., Alderman N., & Burgess P. (1998). The development of an ecologically valid test for assessing pat...