This study aimed to evaluate the efficacy of the Life Therapy Review (LTR) and the Significant Specific Life Events Therapy (SSLET) on the autobiographical memories and the mood state in patients with schizophrenia. 30 patients with schizophrenia were randomly assigned to a LTR group (n= 15) or SSLET group (n=15). Evaluations were made before and after treatment. The results show that both therapies increase autobiographical memory specificity. On the other hand, depressive symptoms only improve in SSLET group. This study provides evidence that autobiographical memory can be trained in schizophrenia, which allows to improve the capacity to encode and store new information. This improvement reduces source attributing mistakes