Sensori-motor neurofeedback improves inhibitory control and induces neural changes: a placebo-controlled, double-blind, event-related potentials study

• Clémence Dousset ^[1] ; Florent Wyckmans ^[1] ; Thibaut Monseigne ^[2] ; Lauréline Fourdin ^[1] ; Romane Boulanger ^[1] ; Sonia Sistiaga ^[1] ; Anaïs Ingels ^[1] ; Hendrik Kajosch ^[1] ; Xavier Noël ^[1] ; Charles Kornreich ^[1] ; Salvatore Campanella ^[1]
  1. [1] Université Libre de Bruxelles

     Université Libre de Bruxelles

     Arrondissement Brussel-Hoofdstad, Bélgica

     
  2. [2] University of Bordeaux

     University of Bordeaux

     Arrondissement de Bordeaux, Francia

     
• Localización: International journal of clinical and health psychology, ISSN 1697-2600, Vol. 24, Nº. 3, 2024, págs. 291-300
• Idioma: inglés
• DOI: 10.1016/j.ijchp.2024.100501
• Enlaces
  • Texto completo
• Resumen

  • Background/Objective Inhibition is crucial for controlling behavior and is impaired in various psychopathologies. Neurofeedback holds promise in addressing cognitive deficits, and experimental research is essential for identifying its functional benefits. This study aimed to investigate whether boosting sensorimotor activity (SMR) improves inhibitory control in a final sample of healthy individuals (N = 53), while exploring the underlying neurophysiological mechanism.

    Method Participants were randomly divided into two groups: one receiving SMR neurofeedback training to enhance sensorimotor activity within the 12–15 Hz frequency range, and the other receiving sham feedback. Inhibition performance and neural correlates were evaluated with a Go-NoGo task before (T0) and after (T1) 10 neurofeedback sessions using event-related potentials. Data were analyzed via ANOVAs and regression analyses.

    Results Compared to placebo, the active group demonstrated higher absolute SMR power (p = 0.040) and improvements in inhibitory control, including faster response times and fewer inhibition errors (p < 0.001, d = 6.06), associated with a larger NoGoP3d amplitude (p < 0.001, d = 3.35). A positive correlation between the increase in SMR power and the rise in NoGoP3d amplitude (β=0.46, p = 0.015) explains 21 % of the observed variance.

    Conclusions Uptraining SMR power is linked to heightened utilization of neural resources for executing optimal inhibition responses. These results uphold its effectiveness in cognitive rehabilitation.

• Referencias bibliográficas
  • Abramovitch, A., Short, T., & Schweiger, A. (2021). The C Factor : Cognitive dysfunction as a transdiagnostic dimension in psychopathology....
  • Alkoby, O., Abu-Rmileh, A., Shriki, O., & Todder, D. (2018). Can we predict who will respond to neurofeedback? A review of the inefficacy...
  • Armstrong, R. A. (2014). When to use the Bonferroni correction. Ophthalmic & Physiological Optics : The Journal Of The British College...
  • Arns, M., Clark, C. R., Trullinger, M., DeBeus, R., Mack, M., & Aniftos, M. (2020). Neurofeedback and attention-deficit/hyperactivity-disorder...
  • Arns, M., Batail, J. M., Bioulac, S., Congedo, M., Daudet, C., Drapier, D., et al. (2017). Neurofeedback: One of today’s techniques in psychiatry?...
  • Barnett, M. J., Doroudgar, S., Khosraviani, V., & Ip, E. J. (2022). Multiple comparisons: To compare or not to compare, that is the question....
  • Bluschke, A., Broschwitz, F., Kohl, S., Roessner, V., & Beste, C. (2016). The neuronal mechanisms underlying improvement of impulsivity...
  • Bursky, M., Egglefield, D. A., Schiff, S. G., Premnath, P., & Sneed, J. R. (2022). Mindfulness-enhanced computerized cognitive training...
  • Campanella, S. (2023). The potential utility of evoked potentials in the treatment of mental illnesses. Psychoradiology, 3. https://doi.org/10.1093/psyrad/kkad024
  • Dehghani, A., Soltanian-Zadeh, H., & Hossein-Zadeh, G. A. (2023). Neural modulation enhancement using connectivity-based EEG neurofeedback...
  • Delacre, M., Lakens, D., & Leys, C. (2017). Why psychologists should by default use Welch’s t-test instead of Student’s t-test. The International...
  • Dousset, C., Kajosch, H., Ingels, A., Schroder, E., Kornreich, C., & Campanella, S. (2020). Preventing relapse in alcohol disorder with...
  • Dousset, C., Ingels, A., Schroder, E., Angioletti, L., Balconi, M., Kornreich, C., et al. (2021). Transcranial direct current stimulation...
  • Egner, T., & Gruzelier, J. H. (2004). EEG biofeedback of low beta band components: Frequency-specific effects on variables of attention...
  • Enriquez-Geppert, S., Konrad, C., Pantev, C., & Huster, R. J. (2010). Conflict and inhibition differentially affect the N200/P300 complex...
  • Gramfort, A., Luessi, M., Larson, E., Engemann, D. A., Strohmeier, D., Brodbeck, C., et al. (2013). MEG and EEG data analysis with MNE -Python....
  • Gruzelier, J. H. (2014). EEG-neurofeedback for optimising performance. I: A review of cognitive and affective outcome in healthy participants....
  • Handy, T. C. (2013). Event-related potentials: A methods handbook. New York: MIT press. https://doi.org/10.4324/9780203123430
  • Hoedlmoser, K., Pecherstorfer, T., Gruber, G., Anderer, P., Doppelmayr, M., Klimesch, W., et al. (2008). Instrumental conditioning of human...
  • Huster, R. J., Enriquez-Geppert, S., Lavallee, C. F., Falkenstein, M., & Herrmann, C. S. (2013). Electroencephalography of response inhibition...
  • Kadosh, K. C., & Staunton, G. (2019). A systematic review of the psychological factors that influence neurofeedback learning outcomes....
  • Kober, S. E., Witte, M., Stangl, M., Valjamae, A., Neuper, C., & Wood, G. (2015). Shutting down sensorimotor interference unblocks the...
  • Luck, S. J. (2014). An introduction to the event-related potential technique (2nd ed). Massachusetts: The MIT Press.
  • Mahrooz, M. H., Fattahzadeh, F., & Gharibzadeh, S. (2023). Decoding the debate: A comparative study of brain-computer interface and neurofeedback....
  • Marvi, N., Haddadnia, J., & Bordbar, M. R. F. (2023). Evaluation of drug abuse on brain function using power spectrum analysis of electroencephalogram...
  • Marzbani, H., Marateb, H. R., & Mansourian, M. (2016). Neurofeedback: A comprehensive review on system design, methodology and clinical...
  • Micoulaud-Franchi, J. A., Daudet, C., & Bioulac, S. (2019). Les enjeux de recherche du neurofeedback dans le trouble insomnie chronique....
  • Pindi, P., Houenou, J., Piguet, C., & Favre, P. (2022). Real-time fMRI neurofeedback as a new treatment for psychiatric disorders: A meta-analysis....
  • Pires, L., Leitao, J., Guerrini, C., & Simoes, M. R. (2014). Event-related brain potentials in the study of inhibition: Cognitive control,...
  • Ribeiro, T. F., Carriello, M. A., de Paula EP Jr, Garcia AC, GLd, Rocha, & Teive, H. A. G. (2023). Clinical applications of neurofeedback...
  • Ros, T., Enriquez-Geppert, S., Zotev, V., Young, K. D., Wood, G., Whitfield-Gabrieli, S., et al. (2020). Consensus on the reporting and experimental...
  • Rubin, M. (2021). When to adjust alpha during multiple testing: A consideration of disjunction, conjunction, and individual testing. Synthese,...
  • Saha, S., Mamun, K. A., Ahmed, K., Mostafa, R., Naik, G. R., Darvishi, S., et al. (2021). Progress in brain computer interface: Challenges...
  • Schabus, M., Heib, D. P., Lechinger, J., Griessenberger, H., Klimesch, W., Pawlizki, A., et al. (2014). Enhancing sleep quality and memory...
  • Schabus, M., Griessenberger, H., Gnjezda, M. T., Heib, D. P., Wislowska, M., & Hoedlmoser, K. (2017). Better than sham? A double-blind...
  • Schulz, K. F., Altman, D. G., & Moher, D. (2010). CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials....
  • Sterman, M. B., & Bowersox, S. S. (1981). Sensorimotor electroencephalogram rhythmic activity: A functional gate mechanism. Sleep, 4(4),...
  • Sterman, M. B. (1996). Physiological origins and functional correlates of EEG rhythmic activities: Implications for self-regulation. Biofeedback...
  • Sterman, M. B. (2000). Basic concepts and clinical findings in the treatment of seizure disorders with EEG operant conditioning. Clinical...
  • Sterman, M. B. (2010). Biofeedback in the treatment of epilepsy. Cleveland Clinic Journal Of Medicine, 77(3), S60–S67. https://doi.org/10.3949/ccjm.77.s3.11
  • Streiner, D. L., & Norman, G. R. (2011). Correction for multiple testing: Is there a resolution? Chest, 140(1), 16–18. https://doi.org/10.1378/chest.11-0523
  • Swick, D., Ashley, V., & Turken, U. (2011). Are the neural correlates of stopping and not going identical? Quantitative meta-analysis...
  • Viviani, G., & Vallesi, A. (2021). EEG-neurofeedback and executive function enhancement in healthy adults: A systematic review. Psychophysiol,...
  • Weber, L. A., Ethofer, T., & Ehlis, A. C. (2020). Predictors of neurofeedback training outcome: A systematic review. NeuroImage. Clinical,...
  • Wessel, J. R. (2018). Prepotent motor activity and inhibitory control demands in different variants of the go/no-go paradigm. Psychophysiol,...
  • Wolpe, N., Hezemans, F. H., Rae, C. L., Zhang, J., & Rowe, J. B. (2022). The pre- supplementary motor area achieves inhibitory control...