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Background: The interplay between physical activity and metabolic health, particularly in diabetes management, is a pivotal area of investigation. This study examines the impact of a three-month moderate aerobic exercise regimen on glycemic control and estrogen levels in young female diabetic patients, aiming to shed light on potential synergies between exercise interventions and hormonal dynamics.
Methods: A one-group pretest-posttest design focused on young diabetic females aged 13 to 18. A structured moderate aerobic exercise program was implemented, comprising warm-up, exercise, and cool-down phases. Pre and post-intervention assessments included blood glucose, estrogen (E2) levels in the follicular phase, and fitness scores, with subsequent comparisons and correlations.
Results: Fifteen young females, with a mean age of 15.07 ± 1.49, participated in the study. The exercise program led to a reduction in glycated hemoglobin (HbA1c) from 8.19 ± 1.11% to 7.23 ± 0.94, a decrease in total daily insulin from 0.58 ± 0.04 to 0.53 ± 0.05, and an increase in estrogen levels from 54.53 ± 4.09 to 4.09. Furthermore, fitness scores improved from 66.53 ± 4.93 to 70.13 ± 4.55. Notably, a significant negative correlation between estrogen levels and glycated hemoglobin (HbA1c) levels (r = -0.813) was observed post-intervention.
Conclusion: This study demonstrates that a three-month moderate aerobic exercise regimen enhances glycemic control and estrogen levels in young diabetic females. Additionally, a robust inverse correlation between estrogen and HbA1c levels highlights a potential interplay between hormonal dynamics and metabolic outcomes in response to exercise interventions.
