Acceso usuarios
J. Tian, J. Wang, W. Quan, B. Lv, J. Liu, C. Hobbie, X. Kong, W. Dong
Abstract Background and objectives Obtaining an objective schizophrenia diagnosis is difficult given current practices. This study aims to evaluate the potential of functional near-infrared spectroscopy (NIRS) in diagnosing individuals with schizophrenia.
Methods This study recruited 100 subjects with schizophrenia (45 males; 55 females) and 70 healthy controls (36 males; 34 females), and analyzed the spectrum of NIRS signals from ETG-4000 Optical Tomography System while subjects took the Verbal Fluency Test (VFT). Two professional psychiatrists performed the wave analysis.
Results There was no statistical difference in the number of words produced during the VFT detected between individuals with schizophrenia and the control group. Results demonstrated that NIRS had an 89.0% sensitivity and 88.6% specificity in identifying individuals with schizophrenia.
Conclusion The results of this study indicated that NIRS spectrums could play a significant role in the diagnosis of schizophrenia by providing an objective index for clinical screening and diagnostic assistance.
