Resumen de Determinants of Quality of Life in Spanish outpatients with schizophrenia spectrum disorders

Juan Ignacio Arrarás Urdániz, Berta Ibáñez Beroiz, I. Basterra Jiménez, N. Pereda, M. Martín, S. Iribarren

• Background and objectives: Quality of Life (QoL) studies of patients with psychosis living in the community and of its determinants can help to improve support offered to patients. This study evaluates QoL in Spanish outpatients with schizophrenia spectrum disorders and attempts to identify the QoL determinants.

  Methods: Sixty-one patients with schizophrenia or schizoaffective disorders and stable disease, completed the generic WHOQOL-BREF, EUROQOL-5D-5L and the specific SQLS-R4 QoL scales and the SCIP (cognitive impairment), SAI-E (insight), and Calgary (depression) scales. SANS (Scales for Assessment of Negative Symptoms) and SAPS (Scales for Assessment of Positive Symptoms) and selected items from the QOLI-BV were also evaluated.

  Frequencies in the clinical, demographic and QoL variables were studied. Univariate and multivariate regression models were fitted to assess how clinical and demographic characteristics influence subjective QoL. Multivariate regression models were fitted with all explanatory variables found to be significant in univariate analysis.