Influencia de los cambios hormonales del ciclo menstrual en la percepción del dolor en las disfunciones temporomandibulares: Una revisión sistemática de la literatura médica

• Autores: R. La Touche, Josué Fernández Carnero, Jorge Pesquera Velasco, J. Mesa
• Localización: Revista de la Sociedad Española del Dolor (SED), ISSN 1134-8046, Vol. 16, Nº. 3, 2009, págs. 153-159
• Idioma: español
• DOI: 10.1016/s1134-8046(09)71007-9
• Títulos paralelos:
  • Influence of hormone changes during the menstrual cycle on pain perception in temporomandibular disorders: A systematic review of the literature
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• Resumen
  • español

    Se dispone de una extensa literatura científica que confirma que las disfunciones temporomandibulares (DTM) presentan una mayor incidencia en mujeres. El objetivo de esta revisión es determinar si el proceso hormonal generado mediante el ciclo menstrual influye en las DTM que presentan sintomatología dolorosa. Se realizó una búsqueda de artículos científicos en las bases datos Medline, Embase, Scielo y CINAHL, entre los años 1970 y 2008. Se incluyeron estudios con diseños de cohortes y de casos y controles, donde se valoraron diversas variables del dolor durante el ciclo menstrual de personas que presentaban DTM. Dos revisores independientes valoraron la calidad de los estudios utilizando la Newcastle-Ottawa Scale. Se seleccionaron para el análisis cualitativo 4 estudios que cumplieron los criterios de inclusión propuestos. Los resultados de los estudios analizados son contradictorios, y por este motivo esta revisión no permite establecer conclusiones afirmativas en relación con el hecho que el factor hormonal femenino influye en la percepción del dolor en las DTM. Consideramos que es necesario realizar una mayor cantidad de estudios donde se investiguen los diversos aspectos del sexo femenino que puedan estar implicados en las DTM.

  • English

    A large body of evidence suggests that temporomandibular joint disorders (TMJD) are much more prevalent in women than in men. The purpose of this systematic review was to examine whether hormone levels during the menstrual cycle infl uence TMJD when painful symptoms are present. A data extraction search strategy was performed in the Medline, Embase, Scielo and CINAHL databases from 1970 to 2008. We included cohort and case-control studies assessing several pain variables in patients with TMJD during the menstrual cycle. The quality of the studies was assessed by two independent reviewers using the Newcastle-Ottawa Scale. Four studies that met the proposed inclusion criteria were included for the qualitative analysis. The results of the studies analyzed are contradictory and consequently do not allow us to conclude that female hormone factors strongly infl uence pain perception in TMJD. Therefore, further studies are required to investigate the various female sex-related factors that could be involved in TMJD.

• Referencias bibliográficas
  • List, T, Dworkin, S F. (1996). Comparing TMD diagnoses and clinical findings at Swedish and US TMD centers using research diagnostic criteria...
  • LeResche, L. (1997). Epidemiology of temporomandibular disorders: implications for the investigation of etiologic factors. Crit Rev Oral Biol...
  • Dworkin, S F, Huggins, KH, LeResche, L, Von Korff, M, Howard, J, Truelove, E. (1990). Epidemiology of signs and symptoms in temporomandibular...
  • Stohler, CS. (1995). Temporomandibular disorders and related pain conditions, progress in pain research and management. IASP Press. Seattle....
  • Schiffman, EL, Fricton, JR, Haley, D. (1992). The relationship of occlusion, parafunctional habits and recent life events to mandibular dysfunction...
  • Velly, AM, Gornitsky, M, Philippe, P. (2003). Contributing factors to chronic myofascial pain: a case-control study. Pain.. 104. 491
  • Berkley, KJ. (1997). Sex differences in pain. Behav Brain Sci.. 20. 371
  • Fillingim, RB, Maixner, W. (1995). Gender differences in the responses to noxious stimuli. Pain Forum. 4. 209
  • Riley, JL 3rd, Robinson, ME, Wise, EA, Myers, CD, Fillingim, RB. (1998). Sex differences in the perception of noxious experimental stimuli:...
  • Marcus, D. (1995). Interrelationships of neurochemicals, estrogen and recurring headache. Pain.. 62. 129
  • Hapidou, EG, Rollman, GB. (1998). Menstrual cycle modulation of ender points. Pain.. 77. 151
  • Riley, JL, Robinson, ME, Wise, EA, Price, D. (1999). A meta-analytic review of pain perception across the menstrual cycle. Pain.. 81. 225
  • Drobek, W, Schoenaers, J, De Laat, A. (2002). Hormone-dependent fluctuations of pressure pain threshold and tactile threshold of the temporalis...
  • Dao, TTT, LeResche, L. (2000). Gender differences in pain. J Orofac Pain.. 14. 169
  • Dao, T T, Lund, J P, Lavigne, GJ. (1994). Pain responses to experimental chewing in myofascial pain patients. J Dent Res.. 73. 1163
  • LeResche, L, Saunders, K, Von Korff, MR, Barlow, W, Dworkin, S F. (1997). Use of exogenous hormones and risk of temporomandibular disorder...
  • Dworkin, S F, LeResche, L. (1992). Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications,...
  • Wells, GA, Shea, B, O'Connell, D, Peterson, J, Welch, V, Losos, M. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized...
  • Vignolo, V, Vedolin, GM, De Araujo Cdos, R, Rodrigues Conti, PC. (2008). Influence of the menstrual cycle on the pressure pain threshold of...
  • Sherman, JJ, LeResche, L, Mancl, LA, Huggins, K, Sage, JC, Dworkin, S F. (2005). Cyclic effects on experimental pain response in women with...
  • LeResche, L, Mancl, L, Sherman, JJ, Gandara, B, Dworkin, S F. (2003). Changes in temporomandibular pain and other symptoms across the menstrual...
  • Isselée, H, De Laat, A, De Mot, B, Lysens, R. (2002). Pressure-pain threshold variation in temporomandibular disorder myalgia over the course...
  • Landi, N, Lombardi, I, Manfredini, D, Casarosa, E, Biondi, K, Gab-banini, M. (2005). Sexual hormone serum levels and temporomandibular disorders:...
  • Sherman, JJ, LeResche, L. (2006). Does experimental pain response vary across the menstrual cycle?: A methodological review. Am J Physiol...
  • Cimino, R, Farella, M, Michelotti, A, Pugliese, R, Martina, R. (2000). Does the ovarian cycle infl uence the pressure-pain threshold of the...