Analysis of errors in verbal fluency tasks in patients with chronic schizophrenia

• Flavia Galaverna ^[1] ; Adrián M. Bueno ^[1] ; Carlos A. Morra ^[2] ; María Roca ^[2] ; Teresa Torralva ^[3]
  1. [1] Universidad Nacional de Córdoba

     Universidad Nacional de Córdoba

     Argentina

     
  2. [2] Consejo Nacional de Investigaciones Científicas y Técnicas

     Consejo Nacional de Investigaciones Científicas y Técnicas

     Argentina

     
  3. [3] Institute of Neurosciences, Favaloro University, Buenos Aires

  Mostrar afiliaciones +
• Localización: European journal of psychiatry, ISSN 0213-6163, Vol. 30, Nº 4, 2016, págs. 305-320
• Idioma: inglés
• Enlaces
  • Texto completo (pdf)
• Resumen

  • Background and Objectives: Even if verbal fluency deficits have been described in Schizophrenia, error pattern in this test has not been analyzed in detail in the literature. The pattern analysis of such errors could contribute to the understanding of the factors that influence poor task performance in schizophrenia. In this study we analyzed the intrusion and perseveration errors in verbal fluency tasks in patients with chronic schizophrenia. Methods: 87 patients diagnosed with Chronic Schizophrenia and 87 healthy controls were included in this investigation and were assessed with four Phonological and Semantic Verbal Fluency tasks. Results The results of this study showed that at least half of schizophrenic patients produced perseverative errors on verbal fluency and about made intrusion errors. The severity of negative symptoms, the severity of Formal Thought Disorder and pharmacological variables were significant moderators to errors in Verbal Fluency performance. Conclusions Errors in Verbal Fluency can be explained by the interaction of different variables in patients with schizophrenia. Schizophrenia is a psychological pathology with great phenomenological complexity and its particularities can only be explained by the consideration of the multiple factors involved in its manifestation.

• Referencias bibliográficas
  • Heinrichs RW, Zakzanis KK. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology. 1998; 12(3): 426-45.
  • Kremen WS, Seidman LJ, Faraone SV, Toomey R, Tsuang MT. The paradox of normal neuropsychological function in schizophrenia. J Abnorm Psychol....
  • Elvevåg B, Weinstock DM, Akil M, Kleinman JE, Goldberg TE. A comparison of verbal fluency tasks in schizophrenic patients and normal controls....
  • Bokat CE, Goldberg TE. Letter and category fluency in schizophrenic patients: a meta-analysis. Schizophr Res. 2003; 64(1): 73-8.
  • Vinogradov S, Kirkland J, Poole JH, Drexler M, Ober BA, Shenaut GK. Both processing speed and semantic memory organization predict verbal...
  • Henry JD, Crawford JR. A meta-analytic review of verbal fluency deficits in schizophrenia relative to other neurocognitive deficits. Cogn...
  • Sumiyoshi C, Sumiyoshi T, Nohara S, Yamashita I, Matsui M, Kurachi M et al. Disorganization of semantic memory underlies alogia in schizophrenia:...
  • Keefe RSE, Eesley CE. Neurocognitive impairment. In JA Lieberman, TS Stroup, DO Perkins (Eds), Textbook of schizophrenia (pp. 245-60). Washington:...
  • Rossell SL, David AS. Are semantic deficits in schizophrenia due to problems with access or storage? Schizophr Res. 2006; 82(2-3): 121-34.
  • Vogel AP, Chenery HJ, Dart CM, Doan B, Tan M, Copland DA. Verbal fluency, semantics, context and symptom complexes in schizophrenia. J Psycholinguist...
  • Ojeda N, Sánchez P, Peña J, Elizagárate E, Yoller AB, Larumbe J et al. Verbal fluency in schizophrenia: does cognitive performance reflect...
  • Juhasz BJ, Chambers D, Shesler LW, Haber A, Kurtz MM. Evaluating lexical characteristics of verbal fluency output in schizophrenia. Psychiatry...
  • Stain HJ, Hodne S, Joa I, Hegelstad WT, Douglas KM, Langveld J et al. The relationship of verbal learning and verbal fluency with written...
  • Sung K, Gordon B, Vannorsdall TD, Ledoux K, Pickett EJ, Pearlson GD et al. Semantic clustering of category fluency in schizophrenia examined...
  • Brébion G, Villalta-Gil V, Autonell J, Cervilla J, Dolz M, Foix A et al. Cognitive correlates of verbal memory and verbal fluency in schizophrenia,...
  • Sumiyoshi C, Ertugrul A, Anil Ya cıo lu AE, Roy A, Jayathilake K, Milby A et al. Language-dependent performance on the letter fluency task...
  • Gourovitch ML, Goldberg TE, Weinberger DR. Verbal fluency deficits in patients with schizophrenia: semantic fluency is differentially impaired...
  • Rossell SL, Rabe-Hesketh SS, Shapleske JS, David AS. Is semantic fluency differentially impaired in schizophrenic patients with delusions?...
  • Allen HA, Liddle PF, Frith CD. Negative features, retrieval processes and verbal fluency in schizophrenia. Br J Psychiatry. 1993; 163: 769-75.
  • Joyce EM, Collinson SL, Crichton P. Verbal fluency in schizophrenia: relationship with executive function, semantic memory and clinical alogia....
  • Rinaldi R, Lefebvre L, Trappenier J. Language, executive functioning and symptomatology – Is fluency a transversal tool in schizophrenia?...
  • Troyer AK, Moscovitch M, Winocur G, Alexander MP, Stuss D. Clustering and switching on verbal fluency: the effects of focal frontaland temporal-lobe...
  • Basso MR, Nasrallah HA, Olson SC, Bornstein RA. Neuropsychological correlates of negative, disorganized and psychotic symptoms in schizophrenia....
  • Kerns JG, Berenbaum H, Barch DM, Banich MT, Stolar N. Word production in schizophrenia and its relationship to positive symptoms. Psychiatry...
  • O’Leary DS, Flaum M, Kesler ML, Flashman LA, Arndt S, Andreasen NC. Cognitive correlates of the negative, disorganized, and psychotic symptom...
  • Docherty AR, Berenbaum H, Kerns JG. Alogia and formal thought disorder: differential patterns of verbal fluency task performance. J Psychiatr...
  • Keefe RS, Goldberg TE, Harvey PD, Gold JM, Poe MP, Coughenour L. The Brief Assessment of Cognition in Schizophrenia: reliability, sensitivity,...
  • Lee MA, Thompson PA, Meltzer HY. Effects of clozapine on cognitive function in schizophrenia. J Clin Psychiatry. 1994; 55 Suppl B: 82-7.
  • Meltzer D. Perspective and the measurement of costs and benefits for cost-effectiveness analysis in schizophrenia. J Clin Psychiatry. 1999;...
  • Blyer CR, Gold J M. Cognitive effects of conventional antipsychotics: another look, in cognitive functioning in schizophrenia: characteristics,...
  • Harvey PD, Keefe RS. Studies of cognitive change in patients with schizophrenia following novel antipsychotic treatment. Am J Psychiatry....
  • Lezak MD, Howieson DB, Loring DW. Neuropsychological assessment. New York: Oxford University Press; 2004.
  • McNamara P, Albert ML. Neuropharmacology of verbal perseveration. Semin Speech Lang. 2004; 25(4): 309-21.
  • Caccappolo-van Vliet E, Miozzo M, Marder K, Stern Y. Where do perseverations come from? Neurocase. 2003; 9(4): 297-307.
  • Sandson J, Albert ML. Varieties of perseveration. Neu ropsychologia. 1984; 22(6): 715-32.
  • Cohen L, Dehaene S. Competition between past and present. Assessment and interpretation of verbal perseverations. Brain. 1998; 121(Pt 9):...
  • Dalla Barba G, Wong C. Encoding specificity and intrusion in Alzheimer’s disease and amnesia. Brain Cogn. 1995; 27(1): 1-16.
  • De Beni R, Palladino P. Intrusion errors in working me mory tasks: are they related to reading comprehension ability? Learning and Individual...
  • Mahone EM, Koth CW, Cutting L, Singer HS, Denckla MB. Executive function in fluency and recall measures among children with Tourette syndrome...
  • Shindler AG, Caplan LR, Hier DB. Intrusions and perseverations. Brain Lang. 1984; 23(1): 148-58.
  • Butters N, Wolfe J, Granholm E, Martone M. An assessment of verbal recall,recognition and fluency abilities in patients with Huntington’s...
  • Kramer JH, Delis DC, Blusewicz MJ, Brandt J, Ober BA, Strauss M. Verbal memory errors in Alzheimer’s and Huntington’s dementias. Developmental...
  • Rouleau I, Imbault H, Laframboise M, Bédard MA. Pattern of intrusions in verbal recall: comparison of Alzheimer’s disease, Parkinson’s disease,...
  • Fuld P, Katzman R, Davies P. Intrusions as a sign of Alzheimer dementia: chemical and pathological verification. Ann Neurol. 1982; 11: 155-9.
  • Loewenstein DA, D’Elia L, Guterman A, Eisdorfer C, Wilkie F, LaRue A et al. The occurrence of different intrusive errors in patients with...
  • Lorscheid T, Thompson SL. Intrusion errors in patients with degenerative or vascular dementia: The cholinergic connection? Dementia. 1991;...
  • Davis KL, Price CC, Kaplan E, Libon DJ. Error analysis of the nine-word California Verbal Learning Test (CVLT-9) among older adults with and...
  • McDowd J, Hoffman L, Rozek E, Lyons KE, Pahwa R, Burns J et al. Understanding verbal fluency in healthy aging, Alzheimer’s disease, and Parkinson’s...
  • Hurks PP, Hendriksen JG, Vles JS, Kalff AC, Feron FJ, Kroes M et al. Verbal fluency over time as a measure of automatic and controlled processing...
  • Woods SP, Conover E, Rippeth JD, Carey CL, Gonzalez R, Marcotte TD et al.; HIV Neurobehavioral Research Center (HNRC) Group. Qualitative aspects...
  • Lebowitz BK, Shear PK, Steed MA, Strakowski SM. Verbal fluency in mania: relationship to number of manic episodes. Neuropsychiatry Neuropsychol...
  • Christodoulou T, Messinis L, Papathanasopoulos P, Frangou S. Dissociable and common deficits in inhibitory control in schizophrenia and bipolar...
  • Fischer-Baum S, Rapp B. Underlying cause(s) of letter perseveration errors. Neuropsychologia. 2012; 50(2): 305-18.
  • Galaverna FS, Morra CA, Bueno AM. Verbal fluency in chronic schizophrenia and severity of psychotic symptoms. Consideration of their relationship...
  • Andreasen NC. The Scale for the Assessment of Positive Symptoms (SAPS). Spanish version. Iowa City, IA: The University of Iowa; 2000.
  • Schwartz S, Baldo J, Graves RE, Brugger P. Pervasive influence of semantics in letter and category fluency: a multidimensional approach. Brain...
  • Goodglas H, Kaplan E, Barresi B. Evaluación de la Afasia y de Trastornos Relacionados. 3ra Edición. Ed. Panamericana. Madrid; 2005.
  • Golden CJ. Stroop Color and Word Test: a Manual for Clinical and Experimental Uses. Chigaco: Skoelting; 1978.
  • Azambuja MJ, Haddad MS, Radanovic M, Barbosa ER, Mansur LL. Semantic, phonologic, and verb fluency in Huntington’s disease. Dementia Neur...
  • Rosser A, Hodges JR. Initial letter and semantic category fluency in Alzheimer’s disease, Huntington’s disease, and progressive supranuclear...
  • Andreasen NC, Arndt S, Swayze V 2nd, Cizadlo T, Flaum M, O’Leary D, et al. Thalamic abnormalities in schizophrenia visualized through magnetic...
  • Henry JD, Phillips LH. Covariates of production and perseveration on tests of phonemic, semantic and alternating fluency in normal aging....
  • Hori H, Noguchi H, Hashimoto R, Nakabayashi T, Omori M, Takahashi S, et al. Antipsychotic medication and cognitive function in schizophrenia.Schizophr...
  • Elie D, Poirier M, Chianetta J, Durand M, Grégoire C, Grignon S. Cognitive effects of antipsychotic dosage and polypharmacy: a study with...
  • Knowles EE, David AS, Reichenberg A. Processing speed deficits in schizophrenia: reexamining the evidence. Am J Psychiatry. 2010; 167(7):...
  • Tandon R, Jibson MD. Safety and tolerability: How do second-generation atypical antipsychotics compare? Current Psychosis & Therapeutics...
  • Tune LE, Strauss ME, Lew MF, Breitlinger E, Coyle JT. Serum levels of anticholinergic drugs and impaired recent memory in chronic schizophrenic...
  • Strauss ME, Reynolds KS, Jayaram G, Tune LE. Effects of anticholinergic medication on memory in schizophrenia. Schizophr Res. 1990; 3(2):...
  • Saykin AJ, Shtasel DL, Gur RE, Kester DB, Mozley LH, Stafiniak P, Gur RC. Neuropsychological deficits in neuroleptic naive patients with first-episode...
  • Casey DE. The relationship of pharmacology to side effects. Journal of Clinical Psychiatry. 1997; 58: 55-62.
  • Richard IH, Justus AW, Greig NH, Marshall F, Kurlan R. Worsening of motor function and mood in a patient with Parkinson’s disease after pharmacologic...
  • Venables P. Input dysfunction in schizophrenia. In B. A. Maher Ed. Progress in Experimental Personality Research. Orlando, FL: Academic Press;...
  • Cromwell RL. (1975). Assessment of schizophrenia. Annual Review of Psychology; 26: 593-619.
  • Chan MW, Yip JT, Lee TM. Differential impairment on measures of attention in patients with paranoid and nonparanoid schizophrenia. J Psychiatr...
  • Heaton R, Paulsen JS, McAdams LA, Kuck J, Zisook S, Braff D et al. Neuropsychological deficits in schizophrenics. Relationship to age,chronicity,...
  • Paulsen JS, Romero R, Chan A, Davis AV, Heaton RK, Jeste DV. Impairment of the semantic network in schizophrenia. Psychiatry Res. 1996; 63:...
  • Zalewski C, Johnson Selfridge MT, Ohriner S, Zarrella K, Seltzer JC. A review of neuropsychological differences between paranoid and non-paranoid...
  • Brazo P, Marié RM, Halbecq I, Benali K, Segard L, Delamillieure P et al. Cognitive patterns in subtypes of schizophrenia. Eur Psychiatry....