To examine the relationship between prior knowledge, situational interest, and recall, 34 college students read 15 paragraphs that contained varying amounts of fictional material, rated how interesting they found each paragraph, and were later assessed on how much of the information they retained. Five of the paragraphs contained fictional items that were accessible, and five paragraphs contained fictional items that were inaccessible. Results indicated that the relationship between prior knowledge was curvilinear but varied based on the accessibility of the novel information. For accessible materials, interest first increased as prior knowledge decreased, but then decreased sharply as prior knowledge lessened. For inaccessible materials, interest did not significantly increase, and decreased at a higher level of prior knowledge relative to accessible materials. Overall, people found accessible materials to be more interesting than inaccessible materials, and interest was not a significant predictor of performance on recall or recognition tasks when prior knowledge was controlled.