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The prolonged consumption of drugs has been associated with neuropsychological and cognitive deficits. The most important deficits are associated with executive functions and memory problems, specifically with prospective memory (PM). This type of memory plays a central role in our daily life. However, there is a lack of studies on the effects of poly drug consumption on prospective memory. In this study we aim to discover to what extent the length and amount of estimated consumption of alcohol, tobacco, cannabis and tranquilizers predicts the scores of self-reported prospective memory, and the scores on two objective tasks designed for this study. Measures included a Spanish version of the UEL Recreational Drug Use Questionnaire and the Prospective Memory Questionnaire, both with objective scores on two experimental tasks. The sample was composed of 164 participants (145 females and 19 males) aged 19- 36 (M = 19.85, SD = 2.21). Stepwise regression analysis showed that years of cannabis consumption explained 13% of self-reported long term PM deficits. Years of alcohol consumption explained 18.4% of total variance of self-rated internally-cued PM deficits. Years of alcohol consumption and estimated amount of alcohol together predicted 30.2% of variance of objective event-based PM tasks. The estimated amount of tobacco and tranquilizers consumption predicted 33.7% of the time-based PM task.
