Stroke is a major cause of morbidity and mortality, often resulting in long-term complications. Post-stroke depression, anxiety, and adjustment disorder are common psychiatric conditions that affect recovery and quality of life. This prospective study examined the incidence of depression and anxiety during the first year after stroke, with attention to demographic, functional, and stroke-related risk factors. A total of 69 stroke patients were followed at Ibn Rochd University Hospital in Casablanca at 1-, 3-, 6-, and 12-months post-stroke. Depression and adjustment disorders were diagnosed using the Mini International Neuropsychiatric Interview (MINI), and anxiety was assessed with the Hamilton Anxiety Scale. Functional and cognitive outcomes were evaluated using the National Institutes of Health Stroke Scale, Modified Rankin Scale, Instrumental Activities of Daily Living scale, and Mini-Mental State Examination. Depression affected 13% of patients at one month, decreasing over time. Anxiety was observed in 14.5% of patients at one month and was associated with cognitive decline (p <.001). Adjustment disorder was diagnosed in 11.6% of patients, particularly among those with major functional dependency (p= .005). These findings underscore the burden of psychological complications following stroke and emphasize the importance of early screening and psychological/psychiatric intervention to enhance recovery and quality of life