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Stroke is the second-leading cause of death worldwide and the third-leading cause when considering both death and disability. Beyond the financial burden it imposes, stroke also has a profound negative impact on mental health. Research indicates that post-stroke disability significantly contributes to the development of depression and anxiety. A cross-sectional study was conducted in Viettri City, Vietnam, from November 2023 to February 2024. Participants included adults diagnosed with poststroke. Data were collected using a structured self-report questionnaire covering demographics, clinical characteristics, functional independence (Barthel Index), anxiety (GAD-7), and depression (PHQ-9) levels. Multivariable logistic regression was employed to identify factors associated with high anxiety and/or depression (HAD). A total of 348 participants, with a mean age of 67.49 years, and females comprising 54.0%, while 26.7% exhibited HAD. Factors significantly associated with these conditions included marital status (OR= 28.88; 95%CI= 2.72-717.24; p= .011), developed fastidiousness (OR= 7.34; 95%CI= 3.67-15.21; p <.001), exercise habits (OR= 2.90; 95%Cl= 1.42-6.07; p= .004), speech ability (OR= 13.10; 95%CI= 1.66-290.24; p= .035), personality types (OR= 0.35; 95%CI= 0.13-0.93;
p= .033), and Barthel Index score (OR= 0.90; 95%CI= 0.85-0.95; p <.001) are significant predictors.
The predictive model, which achieved an AUC of 89.6%, facilitated the development of a nomogram for straightforward assessment of HAD status. Marital status, developed fastidiousness, exercise habits, speech habits, personality traits and Barthel Index emerged as significant predictors of anxiety and depression among stroke patients. Addressing these factors through targeted interventions could potentially mitigate mental health challenges and improve overall outcomes for stroke survivors
